TNF alpha (TNF706 + P/T2), 0.2mg/mL — image 1 of 2

Product details

TNF alpha (TNF706 + P/T2), 0.2mg/mL

Catalog number BNUB0707-100

Price for BNUB0707-100

Size / count 1x 100 µL

About this product

TNF alpha is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha causes cytolysis of certain transformed cells. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Specifications

Catalog number: BNUB0707-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: APC1; Cachectin; Differentiation inducing factor (DIF) ; Macrophage cytotoxic factor (MCF) ; Necrosin; TNF alpha; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precursor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TNF
Gene ID: 7124
NCBI Gene ID: 241570
UniProt: P01375
Swiss Prot: P01375
Host: Mouse
Species Reactivity: Cat, Dog, Human, Mouse, Rabbit, Rat, Zebrafish
Reactivity: TNF-Alpha
Immunogen: Recombinant N-terminal fragment of human TNF-?
Target Antigen: TNF-Alpha
Clonality: Monoclonal
Clone: TNF706
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (verified) |IHC, FFPE (verified)
Field of Research: Cytokines, Immunology
Positive Control: HeLa, HL-60, or A431 cells. Macrophages in lymph node or Tonsil
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 17 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgM, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for TNF alpha (TNF706 + P/T2), 0.2mg/mL?

The catalog number for TNF alpha (TNF706 + P/T2), 0.2mg/mL is BNUB0707-100.

What sizes are available for TNF alpha (TNF706 + P/T2), 0.2mg/mL?

TNF alpha (TNF706 + P/T2), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is TNF alpha (TNF706 + P/T2), 0.2mg/mL in stock?

TNF alpha (TNF706 + P/T2), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TNF alpha (TNF706 + P/T2), 0.2mg/mL?

TNF alpha (TNF706 + P/T2), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for TNF alpha (TNF706 + P/T2), 0.2mg/mL?

Estimated delivery time for TNF alpha (TNF706 + P/T2), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TNF alpha (TNF706 + P/T2), 0.2mg/mL?

The safety data sheet for TNF alpha (TNF706 + P/T2), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e1006d3/msds/bnub0707-100.pdf.

What is TNF alpha (TNF706 + P/T2), 0.2mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.