TNF alpha (TNF706 + P/T2), 1mg/mL

Catalog number BNUM0707-50

Price for BNUM0707-50

Size / count 1x 50 µL

About this product

TNF alpha is a protein secreted by lipopolysaccharide-stimulated macrophages, and causes tumor necrosis when injected into tumor bearing mice. TNF alpha exists as a multimer of two, three, or five non-covalently linked units, but shows a single 17 kDa band following SDS PAGE under non-reducing conditions. TNF alpha causes cytolysis of certain transformed cells. Although it has little effect on many cultured normal human cells, TNF alpha appears to be directly toxic to vascular endothelial cells. Other actions of TNF alpha include stimulating growth of human fibroblasts and other cell lines, activating polymorphonuclear neutrophils and osteoclasts, and induction of interleukin 1, prostaglandin E2 and collagenase production. TNF alpha is currently being evaluated in treatment of certain cancers and AIDS Related Complex.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Specifications

Catalog number: BNUM0707-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: APC1; Cachectin; Differentiation inducing factor (DIF) ; Macrophage cytotoxic factor (MCF) ; Necrosin; TNF alpha; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precursor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TNF
Gene ID: 7124
NCBI Gene ID: 241570
UniProt: P01375
Swiss Prot: P01375
Host: Mouse
Species Reactivity: Cat, Dog, Human, Mouse, Rabbit, Rat, Zebrafish
Reactivity: TNF-Alpha
Immunogen: Recombinant N-terminal fragment of human TNF-? (TNF706) ; Peptide corresponding to aa115-130 of human TNF-? (P/T2)
Target Antigen: TNF-Alpha
Clonality: Monoclonal
Clone: TNF706 P/T2
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cytokines, Immunology
Positive Control: HeLa, HL-60, or A431 cells. Macrophages in lymph node or Tonsil or Histiocytoma
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 17 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgM
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for TNF alpha (TNF706 + P/T2), 1mg/mL?

The catalog number for TNF alpha (TNF706 + P/T2), 1mg/mL is BNUM0707-50.

What sizes are available for TNF alpha (TNF706 + P/T2), 1mg/mL?

TNF alpha (TNF706 + P/T2), 1mg/mL is available in the following size(s): 1x 50 µL.

Is TNF alpha (TNF706 + P/T2), 1mg/mL in stock?

TNF alpha (TNF706 + P/T2), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TNF alpha (TNF706 + P/T2), 1mg/mL?

TNF alpha (TNF706 + P/T2), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TNF alpha (TNF706 + P/T2), 1mg/mL?

Estimated delivery time for TNF alpha (TNF706 + P/T2), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TNF alpha (TNF706 + P/T2), 1mg/mL?

The safety data sheet for TNF alpha (TNF706 + P/T2), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101c5c/msds/bnum0707-50.pdf.

What is TNF alpha (TNF706 + P/T2), 1mg/mL used for?

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.