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Product details

TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL

Catalog number BNC881123-100

Price for BNC881123-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a 63 kDa protein, which is identified as TOX3. It contains a high mobility group (HMG) -box, which regulates calcium-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB) . TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881123-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
TOX3; CAG trinucleotide repeat-containing gene F9 protein; CAGF9; TOX high mobility group box family member 3; Trinucleotide repeat containing 9 (TNRC9)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TOX3
Gene ID
27324
NCBI Gene ID
460789
UniProt
O15405
Swiss Prot
O15405
Host
Mouse
Species Reactivity
Human
Reactivity
TOX3
Immunogen
Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Target Antigen
TOX3
Clonality
Monoclonal
Clone
TOX3/1123
Type
Primary
Source
Animal
Origin
Animal
Applications
WB (verified)
Field of Research
Signal transduction
Positive Control
SH-SY5Y, MDA-MB-435 cells. Brain or breast or gastric Carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
63 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL?

The catalog number for TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL is BNC881123-100.

What sizes are available for TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL?

TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL in stock?

TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL?

TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL?

The safety data sheet for TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TOX3 (TOX3/1123), CF488A conjugate, 0.1mg/mL used for?

This antibody recognizes a 63 kDa protein, which is identified as TOX3. It contains a high mobility group (HMG) -box, which regulates calcium-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB) . TOX3 appears to be associated with breast cance

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

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