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Product details
Catalog number BNUB0247-500
Price for BNUB0247-500
Size / count 1x 500 µL
This MAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to regulate transcription in smooth muscle. During embryogenesis, transgelin is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. Transgelin is downregulated in several transformed cell lines, indicating that a reduction of transgelin expression may be an early indicator of the onset of transformation. Transgelin also binds Actin, causing Actin fibers to gel within minutes of binding. Binding of transgelin to Actin occurs at a ratio of 1:6 Actin monomers. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Transgelin / SM22-alpha (TAGLN/247), 0.2mg/mL is BNUB0247-500.
Transgelin / SM22-alpha (TAGLN/247), 0.2mg/mL is available in the following size(s): 1x 500 µL.
Transgelin / SM22-alpha (TAGLN/247), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Transgelin / SM22-alpha (TAGLN/247), 0.2mg/mL is manufactured by Biotium.
Estimated delivery time for Transgelin / SM22-alpha (TAGLN/247), 0.2mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Transgelin / SM22-alpha (TAGLN/247), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e10287a/msds/bnub0247-500.pdf.
This MAb recognizes a 22 kDa protein, identified as Transgelin, also designated SM22-alpha. It may cross-react with SM22-beta. Transgelin is expressed abundantly in smooth muscle cells. The human transgelin gene encodes a 201 amino acid protein that contains nuclear factor-binding motifs known to re
Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.
