- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
Product details
Catalog number BNC810419-100
Price for BNC810419-100
Size / count 1x 100 µL
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II) . Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all have the same amino acid sequence at their active sites and their activity is calcium-dependent. The protein encoded by this gene acts as a monomer, is induced by retinoic acid, and appears to be involved in apoptosis. Finally, the encoded protein is the autoantigen implicated in celiac disease. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD), a genetic, immunologically mediated small bowel enteropathy that causes malabsorption. TGase II is implicated in programmed cell death, signal transduction, drug-resistance, cell growth, endocytosis, insulin secretion, cell adhesion, cataract formation, and wound healing.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Transglutaminase II (TGM2/419), CF680R conjugate, 0.1mg/mL is BNC810419-100.
Transglutaminase II (TGM2/419), CF680R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
Transglutaminase II (TGM2/419), CF680R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Transglutaminase II (TGM2/419), CF680R conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for Transglutaminase II (TGM2/419), CF680R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Transglutaminase II (TGM2/419), CF680R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0295061270361e0ffd5b/msds/bnc810419-100.pdf.
Recognizes a 77-85 kDa protein, identified as cellular or tissue transglutaminase II (TGase II) . Transglutaminases are enzymes that catalyze the crosslinking of proteins by epsilon gamma glutamyl lysine isopeptide bonds. While the primary structure of transglutaminases is not conserved, they all ha
Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.
Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.
Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.
