TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL

Catalog number BNUB0806-500

Price for BNUB0806-500

Size / count 1x 500 µL

About this product

This antibody reacts with a 75 kDa melanocyte-specific gene product, identified as Tyrosinase-related protein-1 (TRP-1) . It is involved in melanin synthesis. TRP1 is present on the melanosomal membranes of melanoma, normal melanocytes and nevi.Recent evidence suggests that TRP-1 is involved in maintaining stability of tyrosinase protein and modulating its catalytic activity. TRP-1 is also involved in maintenance of melanosome ultrastructure and affects melanocyte proliferation and cell death. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB0806-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 5, 6 dihydroxyindole 2 carboxylic acid oxidase, 6-dihydroxyindole-2-carboxylic acid oxidase, Associated with iris pigmentation, CAS2, Catalase B (CATB), DHICA oxidase, Glycoprotein75 (GP75), Melanoma antigen gp75, Tyrosinase-related protein 1 (TYRP1), TYRRP
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TYRP1
Gene ID: 7306
NCBI Gene ID: 270279
UniProt: P17643
Swiss Prot: P17643
Host: Mouse
Species Reactivity: Human, Mouse
Reactivity: TRP1
Immunogen: SK-MEL-23 cells
Target Antigen: TRP1
Clonality: Monoclonal
Clone: TA99
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |IF (published) |IHC, FFPE (published) |IHC, frozen (published) |IP (published)
Field of Research: Cancer
Positive Control: SK-MEL-23, SK-MEL-19, SK-MEL-30 cells or Melanoma.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 75 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Invest Dermatol (1985) 85:169-174. (IP; IHC, frozen) PNAS USA (1987) 84, 4200-4204. (in vivo imaging melanoma) J Exp Med (1995) 182: 1609-1614. (functional studies) J Cell Biol (2015) 209(4): 563-577. (Flow, surface; IF) J Cell Mol Med (2017) 21(4): 802-815. (IHC, FFPE)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL?

The catalog number for TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL is BNUB0806-500.

What sizes are available for TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL?

TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL in stock?

TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL?

TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL?

Estimated delivery time for TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL?

The safety data sheet for TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TYRP1 (Tyrosinase Related Protein 1) (TA99), 0.2mg/mL used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.