JunD Recombinant Rabbit Monoclonal Antibody [JE59-51]

Catalog number HA722913

Price for HA722913

Size / count 100 µL

About this product

Transcription factor JunD is a protein that in humans is encoded by the JUND gene. The protein encoded by this intronless gene is a member of the JUN family, and a functional component of the AP1 transcription factor complex. It has been proposed to protect cells from p53-dependent senescence and apoptosis. Alternate translation initiation site usage results in the production of different isoforms. The dominant negative mutant variant of JunD, known as ΔJunD or Delta JunD, is a potent antagonist of the ΔFosB transcript, as well as other forms of AP-1-mediated transcriptional activity. In the nucleus accumbens, ΔJunD directly opposes many of the neurological changes that occur in addiction (i.e., those induced by ΔFosB). ΔFosB inhibitors (drugs that oppose its action) may be an effective treatment for addiction and addictive disorders. Being an unnatural genetic variant, deltaJunD has not been observed in humans. JunD has been shown to interact with ATF3, MEN1, DNA damage-inducible transcript 3 and BRCA1.

Specifications

Catalog number: HA722913
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Activator protein 1 antibody AP 1 antibody AP1 antibody Jun D antibody jun D proto oncogene antibody Jund antibody JunD FL isoform antibody JUND_HUMAN antibody Transcription factor jun D antibody Transcription factor jun-D antibody
Abbreviation: JUND
Swiss Prot: P17535 Human, P15066 Mouse, P52909 Rat
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein.
Isotype: IgG
Clone: JE59-51
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: HeLa cell lysate, Jurkat cell lysate, C2C12 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, HeLa, C2C12, mouse brain tissue, rat brain tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 35 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for JunD Recombinant Rabbit Monoclonal Antibody [JE59-51]?

The catalog number for JunD Recombinant Rabbit Monoclonal Antibody [JE59-51] is HA722913.

What sizes are available for JunD Recombinant Rabbit Monoclonal Antibody [JE59-51]?

JunD Recombinant Rabbit Monoclonal Antibody [JE59-51] is available in the following size(s): 100 µL.

Is JunD Recombinant Rabbit Monoclonal Antibody [JE59-51] in stock?

JunD Recombinant Rabbit Monoclonal Antibody [JE59-51] is currently made to order / not held in immediate stock. Contact us for lead time.

What is JunD Recombinant Rabbit Monoclonal Antibody [JE59-51] used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.