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Product details

TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0907-100

Price for BNCB0907-100

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Size / count 1x 100 µL

About this product

Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1 (TTF-1) . TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0907-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BCH|Benign chorea|BHC|Homeobox protein Nkx2.1|NK2 homeobox 1|NKX2.1|NKX2A|TEBP|Thyroid nuclear factor-1|Thyroid specific enhancer binding protein|Thyroid transcription factor-1 (TTF-1) |Tin man|TITF1|TTF-1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NKX2-1
Gene ID
7080
NCBI Gene ID
94367
UniProt
P43699
Swiss Prot
P43699
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
NKX2.1|TTF-1
Immunogen
Rat full length TTF-1 recombinant protein (8G7G3/1) ; Recombinant TTF-1 protein (NX2.1/690)
Target Antigen
NKX2.1 | TTF-1
Clonality
Monoclonal
Clone
8G7G3/1 NX2.1/690
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Transcription factors
Positive Control
MAD109, MLE-15, H441-4, or H345 cells. Normal thyroid or lung.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
40 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL?

The catalog number for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL is BNCB0907-100.

What sizes are available for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL?

TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL in stock?

TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL?

TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL?

The safety data sheet for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e0ffef5/msds/bncb0907-100.pdf.

What is TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), Biotin conjugate, 0.1mg/mL used for?

Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1 (TTF-1) . TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidne

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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