TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL — image 1 of 2

Product details

TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL

Catalog number BNC880907-500

Price for BNC880907-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1 (TTF-1) . TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC880907-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BCH|Benign chorea|BHC|Homeobox protein Nkx2.1|NK2 homeobox 1|NKX2.1|NKX2A|TEBP|Thyroid nuclear factor-1|Thyroid specific enhancer binding protein|Thyroid transcription factor-1 (TTF-1) |Tin man|TITF1|TTF-1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NKX2-1
Gene ID: 7080
NCBI Gene ID: 94367
UniProt: P43699
Swiss Prot: P43699
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Reactivity: NKX2.1|TTF-1
Immunogen: Rat full length TTF-1 recombinant protein (8G7G3/1) ; Recombinant TTF-1 protein (NX2.1/690)
Target Antigen: NKX2.1 | TTF-1
Clonality: Monoclonal
Clone: 8G7G3/1 NX2.1/690
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Transcription factors
Positive Control: MAD109, MLE-15, H441-4, or H345 cells. Normal thyroid or lung.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 40 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG' s
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL?

The catalog number for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL is BNC880907-500.

What sizes are available for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL?

TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL in stock?

TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL?

TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL?

The safety data sheet for TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102886/msds/bnc880907-500.pdf.

What is TTF-1 / NKX2.1 (8G7G3/1 + NX2.1/690), CF488A conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.