TEAD1 Recombinant Rabbit Monoclonal Antibody [JE45-37]

Catalog number HA722144

Price for HA722144

Size / count 100 µL

About this product

Transcriptional enhancer factor TEF-1 also known as TEA domain family member 1 (TEAD1) and transcription factor 13 (TCF-13) is a protein that in humans is encoded by the TEAD1 gene. TEAD1 was the first member of the TEAD family of transcription factors to be identified. TEAD1 is expressed in various tissues including skeletal muscle, pancreas, placenta, lung, and heart. Analysis of cancer transcriptome databases (www.ebi.ac.uk/gxa) showed that TEAD1 is dysregulated in several types of cancers. First in Kaposi sarcoma there is a 300-fold increase in TEAD1 levels. Moreover, the increase of TEAD expression can be detected in basal-like breast cancers, fallopian tube carcinoma, and germ cell tumors. Otherwise, in other types of cancer TEAD expression is decreased, for example in other breast cancer types and in renal or bladder cancers. This dual role can be explained by the different targets and the differential regulation of target genes by TEAD transcription factors. Finally recent studies showed that TEAD1 and YAP in ovarian cancer can induces cell stemness and chemoresistance. And that genetic variant of TEAD protein and YAP are enriched in some cancers.

Specifications

Catalog number: HA722144
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: AA antibody Atrophia areata peripapillary chorioretinal degeneration antibody NTEF 1 antibody NTEF-1 antibody NTEF1 antibody Protein GT IIC antibody Protein GT-IIC antibody REF 1 antibody REF1 antibody SV40 transcriptional enhancer factor antibody TCF 13 antibody TCF-13 antibody TCF13 antibody TEA domain family member antibody TEA domain family member 1 (SV40 transcriptional enhancer factor) antibody TEA domain family member 1 antibody TEAD 1 antibody TEAD 1 protein antibody TEAD-1 antibody TEAD1 antibody TEAD1 protein antibody TEAD1_HUMAN antibody TEF 1 antibody TEF1 antibody Transcription factor 13 (SV40 transcriptional enhancer factor) antibody Transcription factor 13 antibody Transcriptional enhancer factor 1 antibody Transcriptional enhancer factor TEF-1 antibody Transcriptional enhancer factor TEF1 antibody
Abbreviation: TEAD1, TCF13, TEF1
Swiss Prot: P28347 Human, P30051 Mouse,
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human TEF1/TEAD-1 aa 200-300.
Isotype: IgG
Clone: JE45-37
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: HeLa cell lysate, A549 cell lysate, 293T cell lysate, SiHa cell lysate, C2C12 cell lysate, L6 cell lysate, human skeletal muscle tissue, human spleen tissue, mouse skeletal muscle tissue, mouse spleen tissue, rat skeletal muscle tissue, rat spleen tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:200-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 48 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for TEAD1 Recombinant Rabbit Monoclonal Antibody [JE45-37]?

The catalog number for TEAD1 Recombinant Rabbit Monoclonal Antibody [JE45-37] is HA722144.

What sizes are available for TEAD1 Recombinant Rabbit Monoclonal Antibody [JE45-37]?

TEAD1 Recombinant Rabbit Monoclonal Antibody [JE45-37] is available in the following size(s): 100 µL.

Is TEAD1 Recombinant Rabbit Monoclonal Antibody [JE45-37] in stock?

TEAD1 Recombinant Rabbit Monoclonal Antibody [JE45-37] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TEAD1 Recombinant Rabbit Monoclonal Antibody [JE45-37] used for?

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.