TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL — image 1 of 3

Product details

TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL

Catalog number BNC400690-500

Price for BNC400690-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 40 kDa, identified as Thyroid transcription factor-1 (TTF-1) . TTF-1 is a member of the NKx2 family of homeodomain transcription factors. It is expressed in epithelial cells of the thyroid gland and the lung. Nuclei from liver, stomach, pancreas, small intestine, colon, kidney, breast, skin, testes, pituitary, prostate, and adrenal glands are unreactive. Anti-TTF-1 is useful in differentiating primary adenocarcinoma of the lung from metastatic carcinomas originating in the breast, mediastinal germ cell tumors, and malignant mesothelioma. It can also be used to differentiate small cell lung carcinoma from lymphoid infiltrates.Loss of TTF-1 expression in non-small cell lung carcinoma has been associated with aggressive behavior of such neoplasms. TTF-1 reactivity is also seen in thyroid malignancies.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC400690-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: BCH|Benign chorea|BHC|Homeobox protein Nkx2.1|NK2 homeobox 1|NKX2.1|NKX2A|TEBP|Thyroid nuclear factor-1|Thyroid specific enhancer binding protein|Thyroid transcription factor-1 (TTF-1) |Tin man|TITF1|TTF-1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NKX2-1
Gene ID: 7080
NCBI Gene ID: 94367
UniProt: P43699
Swiss Prot: P43699
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Reactivity: NKX2.1|TTF-1
Immunogen: Recombinant TTF-1 protein
Target Antigen: NKX2.1 | TTF-1
Clonality: Monoclonal
Clone: NX2.1/690
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Transcription factors
Positive Control: MAD109, MLE-15, H441-4, or H345 cells. Normal thyroid or lung.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 40 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL?

The catalog number for TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL is BNC400690-500.

What sizes are available for TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL?

TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL in stock?

TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL?

TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL?

The safety data sheet for TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is TTF-1 / NKX2.1 (NX2.1/690), CF640R conjugate, 0.1mg/mL used for?

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.