Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL

Catalog number BNC040812-100

Price for BNC040812-100

Size / count 1x 100 µL

About this product

Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC040812-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ATN, CMM8, LB24-AB, Monophenol monooxygenase, OCA1, OCA1A, Oculocutaneous albinism IA, SHEP3, SK29-AB, Tumor rejection antigen AB, TYR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TYR
Gene ID: 7299
NCBI Gene ID: 503555
UniProt: P14679
Swiss Prot: P14679
Host: Mouse
Species Reactivity: Human
Reactivity: Tyrosinase
Immunogen: Recombinant human TYR protein
Target Antigen: Tyrosinase
Clonality: Monoclonal
Clone: OCA1/812
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: SK-MEL-19, SK-MEL-30 cells or Melanoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70-80 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL?

The catalog number for Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL is BNC040812-100.

What sizes are available for Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL?

Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL in stock?

Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL?

Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Tyrosinase (OCA1/812), CF405S conjugate, 0.1mg/mL used for?

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.