Tyrosinase (T311 + OCA1/812), 0.2mg/mL

Catalog number BNUB0908-100

Price for BNUB0908-100

Size / count 1x 100 µL

About this product

Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB0908-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ATN, CMM8, LB24-AB, Monophenol monooxygenase, OCA1, OCA1A, Oculocutaneous albinism IA, SHEP3, SK29-AB, Tumor rejection antigen AB, TYR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TYR
Gene ID: 7299
NCBI Gene ID: 503555
UniProt: P14679
Swiss Prot: P14679
Host: Mouse
Species Reactivity: Human
Reactivity: Tyrosinase
Immunogen: Recombinant tyrosinase protein (T311) ; Recombinant human TYR protein (OCA1/812)
Target Antigen: Tyrosinase
Clonality: Monoclonal
Clone: T311 OCA1/812
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer
Positive Control: SK-MEL-19, SK-MEL-30 cells or Melanoma.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 70-80 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG' s
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for Tyrosinase (T311 + OCA1/812), 0.2mg/mL?

The catalog number for Tyrosinase (T311 + OCA1/812), 0.2mg/mL is BNUB0908-100.

What sizes are available for Tyrosinase (T311 + OCA1/812), 0.2mg/mL?

Tyrosinase (T311 + OCA1/812), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is Tyrosinase (T311 + OCA1/812), 0.2mg/mL in stock?

Tyrosinase (T311 + OCA1/812), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tyrosinase (T311 + OCA1/812), 0.2mg/mL?

Tyrosinase (T311 + OCA1/812), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for Tyrosinase (T311 + OCA1/812), 0.2mg/mL?

Estimated delivery time for Tyrosinase (T311 + OCA1/812), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Tyrosinase (T311 + OCA1/812), 0.2mg/mL?

The safety data sheet for Tyrosinase (T311 + OCA1/812), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Tyrosinase (T311 + OCA1/812), 0.2mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.