Tyrosinase (T311), CF640R conjugate, 0.1mg/mL — image 1 of 2

Product details

Tyrosinase (T311), CF640R conjugate, 0.1mg/mL

Catalog number BNC400012-100

Price for BNC400012-100

Size / count 1x 100 µL

About this product

Recognizes a cluster of proteins between 70-80 kDa, identified as tyrosinase. Occasionally a minor band at 55 kDa is also detected. This MAb shows no cross-reaction with MAGE-1 and tyrosinase-related protein 1, TRP-1/gp75. Tyrosinase is a copper-containing metalloglycoprotein that catalyzes several steps in the melanin pigment biosynthetic pathway; the hydroxylation of tyrosine to L-3,4-dihydroxy-phenylalanine (dopa), and the subsequent oxidation of dopa to dopaquinone. Mutations of the tyrosinase gene occur in various forms of albinism. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Staining of melanomas with this MAb shows tyrosinase in melanotic as well as amelanotic variants. This MAb is a useful marker for melanocytes and melanomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC400012-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ATN, CMM8, LB24-AB, Monophenol monooxygenase, OCA1, OCA1A, Oculocutaneous albinism IA, SHEP3, SK29-AB, Tumor rejection antigen AB, TYR
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TYR
Gene ID: 7299
NCBI Gene ID: 503555
UniProt: P14679
Swiss Prot: P14679
Host: Mouse
Species Reactivity: Human
Reactivity: Tyrosinase
Immunogen: Recombinant tyrosinase protein
Target Antigen: Tyrosinase
Clonality: Monoclonal
Clone: T311
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (published) |ELISA (published) |IHC, FFPE (verified) |IP (published) |WB (published)
Field of Research: Cancer
Positive Control: SK-MEL-19, SK-MEL-30 cells or Melanoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 70-80 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Clin Pathol (2001) 54:196-200. (IHC, FFPE) PNAS USA (1995) 92: 8125-8129. (WB, IHC, ELISA) J Biol Chem (2001) 276(15): 11933-11938. (WB, IP) Cytometry Part A (2012) 81A: 374381. (Flow, intracellular)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for Tyrosinase (T311), CF640R conjugate, 0.1mg/mL?

The catalog number for Tyrosinase (T311), CF640R conjugate, 0.1mg/mL is BNC400012-100.

What sizes are available for Tyrosinase (T311), CF640R conjugate, 0.1mg/mL?

Tyrosinase (T311), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Tyrosinase (T311), CF640R conjugate, 0.1mg/mL in stock?

Tyrosinase (T311), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tyrosinase (T311), CF640R conjugate, 0.1mg/mL?

Tyrosinase (T311), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Tyrosinase (T311), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Tyrosinase (T311), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Tyrosinase (T311), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Tyrosinase (T311), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Tyrosinase (T311), CF640R conjugate, 0.1mg/mL used for?

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.