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Product details

UACA / Nucling (AE-5), 1mg/mL

Catalog number BNUM0956-50

Price for BNUM0956-50

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Size / count 1x 50 µL

About this product

UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM0956-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Nuclear membrane binding protein; Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) ; NUCLING
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
UACA
Gene ID
55075
NCBI Gene ID
108049
UniProt
Q9BZF9
Swiss Prot
Q9BZF9
Host
Mouse
Species Reactivity
Human, Mouse
Reactivity
Nucling|UACA
Immunogen
Nuclei of myeloid leukemia biopsy cells
Target Antigen
Nucling | UACA
Clonality
Monoclonal
Clone
AE-5
Type
Primary
Source
Animal
Origin
Animal
Applications
WB (verified)
Field of Research
Apoptosis
Positive Control
HeLa or 293T cells. Highly expressed in skeletal muscle, heart, kidney and pancreas. Also expressed in epidermal melanocytes, eye muscles and thyroid follicular cells.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
160 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for UACA / Nucling (AE-5), 1mg/mL?

The catalog number for UACA / Nucling (AE-5), 1mg/mL is BNUM0956-50.

What sizes are available for UACA / Nucling (AE-5), 1mg/mL?

UACA / Nucling (AE-5), 1mg/mL is available in the following size(s): 1x 50 µL.

Is UACA / Nucling (AE-5), 1mg/mL in stock?

UACA / Nucling (AE-5), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures UACA / Nucling (AE-5), 1mg/mL?

UACA / Nucling (AE-5), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for UACA / Nucling (AE-5), 1mg/mL?

Estimated delivery time for UACA / Nucling (AE-5), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for UACA / Nucling (AE-5), 1mg/mL?

The safety data sheet for UACA / Nucling (AE-5), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e1001f9/msds/bnum0956-50.pdf.

What is UACA / Nucling (AE-5), 1mg/mL used for?

UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also late

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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