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Product details

UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0956-100

Price for BNCB0956-100

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Size / count 1x 100 µL

About this product

UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0956-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Nuclear membrane binding protein; Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) ; NUCLING
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
UACA
Gene ID
55075
NCBI Gene ID
108049
UniProt
Q9BZF9
Swiss Prot
Q9BZF9
Host
Mouse
Species Reactivity
Human, Mouse
Reactivity
Nucling|UACA
Immunogen
Nuclei of myeloid leukemia biopsy cells
Target Antigen
Nucling | UACA
Clonality
Monoclonal
Clone
AE-5
Type
Primary
Source
Animal
Origin
Animal
Applications
WB (verified)
Field of Research
Apoptosis
Positive Control
HeLa or 293T cells. Highly expressed in skeletal muscle, heart, kidney and pancreas. Also expressed in epidermal melanocytes, eye muscles and thyroid follicular cells.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
160 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL?

The catalog number for UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL is BNCB0956-100.

What sizes are available for UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL?

UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL in stock?

UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL?

UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL?

The safety data sheet for UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0298061270361e100e31/msds/bncb0956-100.pdf.

What is UACA / Nucling (AE-5), Biotin conjugate, 0.1mg/mL used for?

UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also late

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

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