UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL

Catalog number BNC470956-100

Price for BNC470956-100

Size / count 1x 100 µL

About this product

UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC470956-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Nuclear membrane binding protein; Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) ; NUCLING
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: UACA
Gene ID: 55075
NCBI Gene ID: 108049
UniProt: Q9BZF9
Swiss Prot: Q9BZF9
Host: Mouse
Species Reactivity: Human, Mouse
Reactivity: Nucling|UACA
Immunogen: Nuclei of myeloid leukemia biopsy cells
Target Antigen: Nucling | UACA
Clonality: Monoclonal
Clone: AE-5
Type: Primary
Source: Animal
Origin: Animal
Applications: WB (verified)
Field of Research: Apoptosis
Positive Control: HeLa or 293T cells. Highly expressed in skeletal muscle, heart, kidney and pancreas. Also expressed in epidermal melanocytes, eye muscles and thyroid follicular cells.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 160 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL?

The catalog number for UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL is BNC470956-100.

What sizes are available for UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL?

UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL in stock?

UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL?

UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL?

The safety data sheet for UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a7061270361e1063da/msds/bnc470956-100.pdf.

What is UACA / Nucling (AE-5), CF647 conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.