UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL

Catalog number BNC471222-500

Price for BNC471222-500

Size / count 1x 500 µL

About this product

UACA (Uveal Autoantigen with Coiled-coil domains and Ankyrin repeats) is a 1,416 amino acid nuclear membrane protein. It was originally identified as an autoantigen in patients with panuveitis, a characteristic of Vogt-Koyanagi-Harada disease, and in patients with Graves' disease. UACA was also later identified as Nucling, an mRNA differentially expressed in F9 embryonal carcinoma cells during cardiac muscle differentiation. UACA appears to function as a pro-apoptotic protein that recruits the apaf-1-pro-caspase-9 complex for the induction of apoptosis to mediate the cell-death pathway.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471222-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Nuclear membrane binding protein; Uveal autoantigen with coiled-coil domains and ankyrin repeats (UACA) ; NUCLING
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: UACA
Gene ID: 55075
NCBI Gene ID: 108049
UniProt: Q9BZF9
Swiss Prot: Q9BZF9
Host: Mouse
Species Reactivity: Human, Mouse
Reactivity: Nucling|UACA
Immunogen: Recombinant human UACA protein
Target Antigen: Nucling | UACA
Clonality: Monoclonal
Clone: UACA/1222
Type: Primary
Source: Animal
Origin: Animal
Applications: WB (verified)
Field of Research: Apoptosis
Positive Control: HeLa or 293T cells. Highly expressed in skeletal muscle, heart, kidney and pancreas. Also expressed in epidermal melanocytes, eye muscles and thyroid follicular cells.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 160 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL?

The catalog number for UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL is BNC471222-500.

What sizes are available for UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL?

UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL in stock?

UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL?

UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL?

The safety data sheet for UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a0061270361e1039b0/msds/bnc471222-500.pdf.

What is UACA / Nucling (UACA/1222), CF647 conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.