TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL — image 1 of 5

Product details

TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL

Catalog number BNC741123-100

Price for BNC741123-100

Size / count 1x 100 µL

About this product

This antibody recognizes a 63 kDa protein, which is identified as TOX3. It contains a high mobility group (HMG) -box, which regulates calcium-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB) . TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC741123-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: TOX3; CAG trinucleotide repeat-containing gene F9 protein; CAGF9; TOX high mobility group box family member 3; Trinucleotide repeat containing 9 (TNRC9)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: TOX3
Gene ID: 27324
NCBI Gene ID: 460789
UniProt: O15405
Swiss Prot: O15405
Host: Mouse
Species Reactivity: Human
Reactivity: TOX3
Immunogen: Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Target Antigen: TOX3
Clonality: Monoclonal
Clone: TOX3/1123
Type: Primary
Source: Animal
Origin: Animal
Applications: WB (verified)
Field of Research: Signal transduction
Positive Control: SH-SY5Y, MDA-MB-435 cells. Brain or breast or gastric Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 63 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL?

The catalog number for TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL is BNC741123-100.

What sizes are available for TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL?

TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL in stock?

TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL?

TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL?

The safety data sheet for TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100744/msds/bnc741123-100.pdf.

What is TOX3 (TOX3/1123), CF740 conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.