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Product details

WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL

Catalog number BNC880856-500

Price for BNC880856-500

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Size / count 1x 500 µL

About this product

Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm s tumors.WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilm s tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilm s tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC880856-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
WT1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
WT1
Gene ID
7490
NCBI Gene ID
591980
UniProt
P19544
Swiss Prot
P19544
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
Wilm' s Tumor 1|WT1
Immunogen
Recombinant protein corresponding to residues 1-181 of human WT1.
Target Antigen
Wilm's Tumor 1 | WT1
Clonality
Monoclonal
Clone
6F-H2
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology, Transcription factors
Positive Control
K562 cells. Wilm s Tumor, mesothelioma or fetal kidney.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
47-55 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL?

The catalog number for WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL is BNC880856-500.

What sizes are available for WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL?

WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL in stock?

WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL?

WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL?

The safety data sheet for WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e100f9c/msds/bnc880856-500.pdf.

What is WT1 (Wilm's Tumor 1) (6F-H2), CF488A conjugate, 0.1mg/mL used for?

Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm s tumors.WT1, a sporadic and familial pedia

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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