WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL — image 1 of 3

Product details

WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL

Catalog number BNC041138-500

Price for BNC041138-500

Size / count 1x 500 µL

About this product

Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm s tumors.WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilm s tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilm s tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC041138-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: WT1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: WT1
Gene ID: 7490
NCBI Gene ID: 591980
UniProt: P19544
Swiss Prot: P19544
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Reactivity: Wilm' s Tumor 1|WT1
Immunogen: Recombinant full length human WT1 protein (WT1/857) ; Recombinant fragment aa1-181 of human WT1 (6F-H2)
Target Antigen: Wilm's Tumor 1 | WT1
Clonality: Monoclonal
Clone: WT1/857 6F-H2
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Developmental biology, Transcription factors
Positive Control: K562 cells. Wilm s Tumor, mesothelioma or fetal kidney.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 47-55 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG' s
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL?

The catalog number for WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL is BNC041138-500.

What sizes are available for WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL?

WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL in stock?

WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL?

WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL?

The safety data sheet for WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is WT1 (Wilm's Tumor 1) (WT1/857 + 6F-H2), CF405S conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.