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Product details

WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL

Catalog number BNC400857-500

Price for BNC400857-500

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Size / count 1x 500 µL

About this product

Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm s tumors.WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilm s tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilm s tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC400857-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
WT1; AWT1; FWT1; GUD; NPHS4; WAGR; Wilms tumor 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
WT1
Gene ID
7490
NCBI Gene ID
591980
UniProt
P19544
Swiss Prot
P19544
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Reactivity
Wilm' s Tumor 1|WT1
Immunogen
Recombinant human WT1 protein
Target Antigen
Wilm's Tumor 1 | WT1
Clonality
Monoclonal
Clone
WT1/857
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology, Transcription factors
Positive Control
K562 cells. Wilm s Tumor, mesothelioma or fetal kidney.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
47-55 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG' s
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL?

The catalog number for WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL is BNC400857-500.

What sizes are available for WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL?

WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL in stock?

WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL?

WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL?

The safety data sheet for WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is WT1 (Wilm's Tumor 1) (WT1/857), CF640R conjugate, 0.1mg/mL used for?

Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm s tumors.WT1, a sporadic and familial pedia

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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