MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL

Catalog number BNC742414-100

Price for BNC742414-100

Size / count 1x 100 µL

About this product

MDM2 is a nuclear phosphoprotein that binds and inhibits transactivation by tumor protein p53. It can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. Overexpression of MDM2 can result in excessive inactivation of tumor protein p53, diminishing its tumor suppressor function. This protein also affects the cell cycle, apoptosis, and tumorigenesis through interactions with other proteins, including retinoblastoma 1 and ribosomal protein L5. Overexpression of MDM2 protein is detected in a variety of cancers. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742414-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: ACTFS; Double minute 2 protein; E3 ubiquitin-protein ligase; Hdm2; HDMX; MDM2; MDM2 oncogene E3 ubiquitin protein ligase; MDM2BP; Mouse Double Minute 2; MTBP; Murine Double Minute Chromosome 2; p53 Binding Protein Mdm2; p53-binding protein Mdm2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MDM2
Gene ID: 4193
NCBI Gene ID: 484551
UniProt: Q00987
Swiss Prot: Q00987
Host: Mouse
Species Reactivity: Human
Reactivity: MDM2
Immunogen: Recombinant human MDM2 protein fragment (around aa 126-254) (exact sequence is proprietary)
Target Antigen: MDM2
Clonality: Monoclonal
Clone: MDM2/2414
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: A549 or HeLa cells. Pancreas.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 90 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL?

The catalog number for MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL is BNC742414-100.

What sizes are available for MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL?

MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL in stock?

MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL?

MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL?

The safety data sheet for MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0295061270361e0ffca3/msds/bnc742414-100.pdf.

What is MDM2 (MDM2/2414), CF740 conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.