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Product details

NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL

Catalog number BNC742547-100

Price for BNC742547-100

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Size / count 1x 100 µL

About this product

The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC742547-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Homeobox protein NK 2 homolog H; Homeobox protein NK-2 homolog H; Homeobox protein Nkx 2.8; Homeobox protein Nkx-2.8; NK 2 homolog 8; NK 2 homolog H; NK2 homeobox 8; NK2 transcription factor related; locus 8; Nkx2 9; Nkx2-8; NKX2.8; NKX28_HUMAN; NKX2G; NKX2H; OTTHUMP00000027959
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NKX2-8
Gene ID
26257
NCBI Gene ID
234763
UniProt
O15522
Swiss Prot
O15522
Host
Mouse
Species Reactivity
Human
Reactivity
NKX2.8
Immunogen
Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)
Target Antigen
NKX2.8
Clonality
Monoclonal
Clone
NKX28/2547
Type
Primary
Source
Animal
Origin
Animal
Applications
WB (verified)
Positive Control
Human Liver, Kidney or Thyroid tissue (IHC).
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
26 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), Bos taurus (bovine)
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL?

The catalog number for NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL is BNC742547-100.

What sizes are available for NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL?

NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL in stock?

NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL?

NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL?

The safety data sheet for NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NKX2.8 (NKX28/2547), CF740 conjugate, 0.1mg/mL used for?

The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patie

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

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