Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL

Catalog number BNC742573-100

Price for BNC742573-100

Size / count 1x 100 µL

About this product

Focal adhesions are identified as areas within the plasma membrane of tissue culture cells that adhere tightly to the underlying substrate. In vivo, these regions are involved in the adhesion of cells to the extracellular matrix. Paxillin and vinculin are cytoskeletal, focal adhesion proteins that are components of a protein complex which links the Actin network to the plasma membrane. Vinculin binding sites have been identified on other cytoskeletal proteins, including talin and alpha-actinin each contain actin binding sites. Reportedly, vinculin is a potential plasma biomarker for Age-related Macular Degeneration (AMD) . The early detection of AMD using novel plasma biomarkers with genetic modeling may enable timely treatment and vision preservation in the elderly. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742573-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CMD1W; CMH15; Epididymis luminal protein 114; HEL114; Metavinculin; MV; MVCL; VCL; VINC
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: VCL
Gene ID: 7414
NCBI Gene ID: 643896
UniProt: P18206
Swiss Prot: P18206
Host: Mouse
Species Reactivity: Human, Mouse
Reactivity: Vinculin
Immunogen: Recombinant fragment (around aa 174-322) of human Vinculin (VCL) protein (exact sequence is proprietary)
Target Antigen: Vinculin
Clonality: Monoclonal
Clone: VCL/2573
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: Human Bladder and Testis.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 117 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL?

The catalog number for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL is BNC742573-100.

What sizes are available for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL?

Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL in stock?

Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL?

Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL?

The safety data sheet for Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Vinculin (Marker of Age-related Macular Degeneration) (VCL/2573), CF740 conjugate, 0.1mg/mL used for?

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.