CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL

Catalog number BNC742673-100

Price for BNC742673-100

Size / count 1x 100 µL

About this product

CD117, also known as c-kit, is a member if the immunoglobin superfamily. It is a receptor tyrosine kinase that is expressed on hematopoietic progenitor cells. It binds to the c-kit ligand KITLG/SCF and has roles in cell survival and cell proliferation. Upon ligand binding, it activates a number of signaling pathways. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742673-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD117; c-Kit; p145; Mast/stem Cell Growth Factor Receptor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: KIT
Gene ID: 3815
NCBI Gene ID: 479754
UniProt: P10721
Swiss Prot: P10721
Host: Mouse
Species Reactivity: Human
Reactivity: C-Kit|CD117
Immunogen: Recombinant full-length human KIT protein
Target Antigen: c-Kit | CD117
Clonality: Monoclonal
Clone: KIT/2673
Type: Primary
Source: Animal
Origin: Animal
Field of Research: Cancer, Signal transduction
Positive Control: Gastrointestinal Stromal Tumor (GIST) or testicular germ cell tumor. Melanocytes in the basal layer of the epidermis and mast cells in the dermis of normal skin.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 145 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL?

The catalog number for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL is BNC742673-100.

What sizes are available for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL?

CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL in stock?

CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL?

CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL?

The safety data sheet for CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors) (KIT/2673), CF740 conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.