CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL

Catalog number BNC742749-100

Price for BNC742749-100

Size / count 1x 100 µL

About this product

DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC742749-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD209; CDSIGN; CIRE; CLEC4L; DC-SIGN; DC-SIGN1; DCSIGN; Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1; HIV GP120 Binding Protein; SIGN-R1; SIGNR5
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD209
Gene ID: 30835
NCBI Gene ID: 278694
UniProt: Q9NNX6
Swiss Prot: Q9NNX6
Host: Rabbit
Species Reactivity: Human
Reactivity: CD209|DC-SIGN
Immunogen: Recombinant full-length human CD209 protein
Target Antigen: CD209 | DC-SIGN
Clonality: Recombinant Monoclonal
Clone: C209/2749R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: THP-1 or HeLa cells (IF/FACS). Human liver or spleen lysate (WB). Human small intestine (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% rBSA, 0.05% azide
Molecular Weight: 45 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), Bos taurus (bovine)
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF740

Frequently Asked Questions

What is the catalog number for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL?

The catalog number for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL is BNC742749-100.

What sizes are available for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL in stock?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL?

CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL?

The safety data sheet for CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD209 / DC-SIGN (Pathogen Receptor on Dendritic Cells) (C209/2749R), CF740 conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.