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Product details

HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL

Catalog number BNC743475-500

Price for BNC743475-500

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Size / count 1x 500 µL

About this product

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six alpha and ten beta chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC743475-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HLA-DPB1; HLA-DQA1; HLA-DQB1; HLA-DRA; HLA-DRB1; HLA-DRB3; HLA-DRB4; HLA-DRB5
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
HLA-DP; HLA-DQ; HLA-DR
Gene ID
3115; 3117; 3122
NCBI Gene ID
347270; 550475; 520048
UniProt
P04440; P01908; P01909; P01920; P01903
Swiss Prot
P04440; P01908; P01909; P01920; P01903
Host
Mouse
Species Reactivity
Human
Reactivity
HLA-Pan|MHCII
Immunogen
Non-T, non-B human acute lymphoblastic leukemia REH6 cells
Target Antigen
HLA-Pan | MHCII
Clonality
Recombinant Monoclonal
Clone
RHLA-Pan/3475
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified)
Positive Control
Raji cells. Tonsil or lymph node
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% rBSA, 0.05% azide
Molecular Weight
33-35 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF740

Frequently Asked Questions

What is the catalog number for HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL?

The catalog number for HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL is BNC743475-500.

What sizes are available for HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL?

HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL in stock?

HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL?

HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL?

Estimated delivery time for HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL?

The safety data sheet for HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is HLA-Pan (MHC II) (rHLA-Pan/3475), CF740 conjugate, 0.1mg/mL used for?

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa) . They are expressed primarily on antigen presenting cells such as B

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

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