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Product details

MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL

Catalog number BNC470960-500

Price for BNC470960-500

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Size / count 1x 500 µL

About this product

This MAb reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of this MAb involves both amino acids as well as sugar moieties. Neuraminidase treatment destroys the antigen. It is a very good tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC470960-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Breast carcinoma-associated antigen DF3; CA15-3; Carcinoma-associated mucin Episialin; Epithelial Membrane Antigen; H23AG; KL-6; MAM6; MUC-1; MUC-1/SEC; MUC-1/X; MUC1-alpha; MUC1-beta; MUC1-CT; MUC1-NT; MUC1/ZD; Mucin 1 cell surface associated; Mucin-1 subunit beta; Peanut-reactive urinary mucin; PEM; PEMT; Polymorphic epithelial mucin; PUM; Tumor-associated epithelial membrane antigen
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MUC1
Gene ID
4582
NCBI Gene ID
89603
UniProt
P15941
Swiss Prot
P15941
Host
Mouse
Species Reactivity
Human
Reactivity
CD227|EMA|Episialin|Mucin 1
Immunogen
Human milk-fat globule membranes (HMFGM)
Target Antigen
CD227 | EMA | Episialin | Mucin 1
Clonality
Recombinant Monoclonal
Clone
RMUC1/960
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Mucins
Positive Control
MCF-7 or MDA-231 cells. Breast, colon, ovarian, endometrial carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
265-400 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL?

The catalog number for MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL is BNC470960-500.

What sizes are available for MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL?

MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL in stock?

MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL?

MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a8061270361e106a73/msds/bnc470960-500.pdf.

What is MUC1 / EMA / CD227 (Epithelial Marker) (rMUC1/960), CF647 conjugate, 0.1mg/mL used for?

This MAb reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of this MAb involves both amino acids as well as sugar moieties. Neuraminidase treatment destroys the antigen. It is a very good tracer agent in CA15.3 as

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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