Calnexin (Endoplasmic Reticulum Marker) (CANX/1541), CF647 conjugate, 0.1mg/mL

About this product

Calnexin is a type-I integral membrane protein of the endoplasmic reticulum (ER) . It is a calcium-binding chaperone protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC471541-100

Size / count

1x 100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

Calnexin; CANX; IP90; Major histocompatibility complex class I antigen-binding protein p88

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

CANX

Gene ID

821

NCBI Gene ID

567968

UniProt

P27824

Swiss Prot

P27824

Host

Mouse

Species Reactivity

Human

Reactivity

Calnexin

Immunogen

Recombinant N-terminal fragment of human Calnexin protein (exact sequence is proprietary)

Target Antigen

Calnexin

Clonality

Monoclonal

Clone

CANX/1541

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, intracellular|IF (verified) |IHC, FFPE (verified) |WB (verified)

Field of Research

Chaperones, Immunology

Positive Control

HeLa, MCF-7 or U2OS cells. Kidney or small intestine.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

67 kDa (predicted) ; 80-90 kDa (observed)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG2b, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF647