Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL

Catalog number BNC471711-100

Price for BNC471711-100

Size / count 1x 100 µL

About this product

Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helicalcoiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. The antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471711-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CMD1I; CSM1; CSM2; DES; Intermediate filament protein
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: DES
Gene ID: 1674
NCBI Gene ID: 594952
UniProt: P17661
Swiss Prot: P17661
Host: Mouse
Species Reactivity: Chicken, Hamster, Human, Mouse, Rat
Reactivity: Desmin
Immunogen: Recombinant human full-length desmin protein
Target Antigen: Desmin
Clonality: Monoclonal
Clone: DES/1711
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Cancer, Cytoskeleton
Positive Control: SJRH30 Cells. Uterus or Leiomyosarcoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 52 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL?

The catalog number for Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL is BNC471711-100.

What sizes are available for Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL?

Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL in stock?

Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL?

Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e1004cc/msds/bnc471711-100.pdf.

What is Desmin (Muscle Cell Marker) (DES/1711), CF647 conjugate, 0.1mg/mL used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.