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Product details

CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL

Catalog number BNC471757-100

Price for BNC471757-100

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Size / count 1x 100 µL

About this product

This MAb recognizes a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B) . Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Unlike other elastases, elastase 3B has little elastolytic activity. Like most of the human elastases, elastase 3B is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein; it has a digestive function in the intestine. Elastase 3B preferentially cleaves proteins after alanine residues. Elastase 3B may also function in the intestinal transport and metabolism of cholesterol. Both elastase 3A and elastase 3B have been referred to as protease E and as elastase 1, and excretion of this protein in fecal material is frequently used as a measure of pancreatic function.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC471757-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Chymotrypsin like elastase family member 3B (CELA3B) ; ELA3B; Elastase IIIB; Protease E
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CELA3B
Gene ID
23436
NCBI Gene ID
728752
UniProt
P08861
Swiss Prot
P08861
Host
Mouse
Species Reactivity
Human
Reactivity
CELA3B|ELA3B
Immunogen
Recombinant human CELA3B protein fragment (aa82-238) (exact sequence is proprietary)
Target Antigen
CELA3B | ELA3B
Clonality
Monoclonal
Clone
CELA3B/1757
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Proteases
Positive Control
Panc-28 or PANC1 cells. Pancreas
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
17 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL?

The catalog number for CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL is BNC471757-100.

What sizes are available for CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL?

CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL in stock?

CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL?

CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b0061270361e10978a/msds/bnc471757-100.pdf.

What is CELA3B / ELA3B (Pancreatic Function Marker) (CELA3B/1757), CF647 conjugate, 0.1mg/mL used for?

This MAb recognizes a protein of ~30 kDa, identified as CELA3B (Chymotrypsin like elastase family member 3B) . Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1,

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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