CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL

Catalog number BNC471779-100

Price for BNC471779-100

Size / count 1x 100 µL

About this product

CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471779-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD8 antigen, alpha polypeptide (p32), T8/Leu-2 T-lymphocyte differentiation antigen, Ly3, LYT3, MAL, T-cell surface glycoprotein CD8 alpha chain
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD8A
Gene ID: 925
NCBI Gene ID: 85258
UniProt: P01732
Swiss Prot: P01732
Host: Rabbit
Species Reactivity: Human
Reactivity: CD8A
Immunogen: Recombinant full-length human CD8a protein
Target Antigen: CD8A
Clonality: Recombinant Monoclonal
Clone: C8/1779R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Field of Research: Immunology
Positive Control: HuT78 or hPBL. Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 32 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG, kappa
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL?

The catalog number for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL is BNC471779-100.

What sizes are available for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL in stock?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029e061270361e103065/msds/bnc471779-100.pdf.

What is CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF647 conjugate, 0.1mg/mL used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.