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Product details

Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL

Catalog number BNC401784-500

Price for BNC401784-500

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Size / count 1x 500 µL

About this product

Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed supealpha-helicalturn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC401784-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
H1 (0) |H1.1|H1.2|H1.3|H1.4|H1.5|H1A|H1F0|H1F1|H1F2|H1F3|H1F4|H1F5|H1FNT|H1FOO|H1FT|H1FV|H1FX|H1t|H1T2|H1X|HANP1|His1|HisC|HIST1|HIST1H1A|HIST1H1B|HIST1H1C|HIST1H1D|HIST1H1E|HIST1H1T|Oocyte-specific histone H1|Testicular H1 histone
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
H1
Gene ID
3005
NCBI Gene ID
226117 & 97358
UniProt
Multiple
Swiss Prot
Multiple
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Reactivity
Histone H1
Immunogen
Recombinant full-length human Histone H1 protein
Target Antigen
Histone H1
Clonality
Recombinant Monoclonal
Clone
HH1/1784R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research
Organelle markers
Positive Control
HeLa, A-431, LNCap or Jurkat cells. Breast carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~30 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG, kappa
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL?

The catalog number for Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL is BNC401784-500.

What sizes are available for Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL?

Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL in stock?

Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL?

Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Histone H1 (Nuclear Marker) (HH1/1784R), CF640R conjugate, 0.1mg/mL used for?

Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed supealpha-helicalturn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) for

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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