• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL

Catalog number BNC401836-100

Price for BNC401836-100

Sign In for Pricing

Size / count 1x 100 µL

About this product

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC401836-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NKX2-2
Gene ID
4821
NCBI Gene ID
516922
UniProt
O95096
Swiss Prot
O95096
Host
Mouse
Species Reactivity
Chicken, Human, Mouse, Rat
Reactivity
NKX2.2
Immunogen
Human full-length recombinant NKX2.2 protein
Target Antigen
NKX2.2
Clonality
Recombinant Monoclonal
Clone
RNX2/294
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology, Transcription factors
Positive Control
Pancreas or Ewing s sarcoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
40-50 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL?

The catalog number for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL is BNC401836-100.

What sizes are available for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL in stock?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL?

The safety data sheet for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF640R conjugate, 0.1mg/mL used for?

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be diff

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

You Might Also Like
Mucin 5AC (MUC5AC) (58M1), CF405S conjugate, 0.1mg/mL
Mucin 5AC (MUC5AC) (58M1), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041003-500
CD11c (HC1/1), CF680R conjugate, 0.1mg/mL
CD11c (HC1/1), CF680R conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC810152-500
CD47 (B6H12.2), CF568 conjugate, 0.1mg/mL
CD47 (B6H12.2), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC680437-100
HSP27 (G3.1), CF647 conjugate, 0.1mg/mL
HSP27 (G3.1), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC470861-100
CD45RO (190-2F2.5), CF405S conjugate, 0.1mg/mL
CD45RO (190-2F2.5), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041081-500
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
Major Vault Protein (MVP) (1032), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880225-100
Cytochrome C (CTC05), CF740 conjugate, 0.1mg/mL
Cytochrome C (CTC05), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740887-500
CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF405S conjugate, 0.1mg/mL
CD8A (Cytotoxic- & Suppressor T-Cell Marker) (C8/1779R), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041779-500