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Product details
Catalog number BNC611492-500
Price for BNC611492-500
Size / count 1x 500 µL
This antibody recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for PAX8 (Renal Cell Marker) (PAX8/1492), CF660R conjugate, 0.1mg/mL is BNC611492-500.
PAX8 (Renal Cell Marker) (PAX8/1492), CF660R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
PAX8 (Renal Cell Marker) (PAX8/1492), CF660R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
PAX8 (Renal Cell Marker) (PAX8/1492), CF660R conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for PAX8 (Renal Cell Marker) (PAX8/1492), CF660R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for PAX8 (Renal Cell Marker) (PAX8/1492), CF660R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b1061270361e109f63/msds/bnc611492-500.pdf.
This antibody recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.
