Neuraminidases (NA) Inhibitor Screening Assay Kit

Specifications

Catalog number

E-BC-D004

Size / count

96 Tests

Dry ice

No

Hazardous

No

Discontinued

No

Target

NA

Type

Fluorometric method

Field of Research

Inhibitor Screening

Assay Principle

Neuraminidases, also known as sialidase, are a family of exoglycans that hydrolyse glycolipids, oligosaccharides and sialic acid residues at the end of glycoproteins. NA is distributed in viruses, bacteria, fungi and vertebrate cells. Viral neuraminidase is one of the important targets of some influenza drugs. Human neuraminidase plays a role in a variety of signaling pathways and is associated with a variety of diseases such as neurodegenerative diseases, cancer, and cardiovascular and cerebrovascular diseases. Therefore, it is important to develop NA inhibitors. The detection principle of this kit is that NA decomsolves the substrate to release fluorescent substances, and the activity can be inhibited by adding NA inhibitor. The inhibition ability of inhibitor can be judged by the fluorescence value.

Assay Performance Time

60 min

Sample Type

Inhibitor

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at -20°C for 12 months with shading light.

Inter CV

2.0-4.0%

Intra CV

1.0-2.0%

Detection Instrument

Fluorescence Microplate Reader