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Product details

N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL

Catalog number BNC681573-500

Price for BNC681573-500

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Size / count 1x 500 µL

About this product

This antibody recognizes a protein of ~140 kDa, identified as N-Cadherin (NCAD), also known as CD325. N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements during development and regulate cell surface adhesion through homotypic adhesion with the same cadherin species. Expression of N-cadherin has been reported on a variety of normal tissues including neuronal, endothelial and muscle cells, and a subpopulation of early hematopoietic progenitor cells. Results aid in the classification of malignant non-carcinomatous neoplasms including mesotheliomas, chordomas, synovial sarcomas, malignant melanomas, epithelioid sarcomas, epithelioid angiosarcomas, clear cell sarcomas as well as serous and endometrioid tumors of the ovary have been demonstrated to be N-cadherin positive, whereas mucinous tumors are negative. Other N-cadherin-positive neoplasms include renal cell carcinomas and some variant breast tumors, including medullary breast carcinomas and sarcomatoid metaplastic breast carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC681573-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Cadherin-2 N cadherin neuronal; Cadherin-2 type 1; Cadherin-2; Calcium dependent adhesion protein neuronal; CD325; CDH2; CDHN; CDw325; N-Cadherin; NCAD
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CDH2
Gene ID
1000
NCBI Gene ID
464829
UniProt
P19022
Swiss Prot
P19022
Host
Mouse
Species Reactivity
Human, Mouse
Reactivity
Cadherin-2|CD325|N-Cadherin
Immunogen
Recombinant human CDH2 intracellular domain (exact sequence is proprietary)
Target Antigen
Cadherin-2 | CD325 | N-Cadherin
Clonality
Monoclonal
Clone
CDH2/1573
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cell adhesion, Developmental biology
Positive Control
HeLa or HUVEC cells. Heart, Pancreas or Cerebral Cortex
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
130-140 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF568

Frequently Asked Questions

What is the catalog number for N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL?

The catalog number for N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL is BNC681573-500.

What sizes are available for N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL?

N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL in stock?

N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL?

N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL?

The safety data sheet for N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0297061270361e100392/msds/bnc681573-500.pdf.

What is N-Cadherin / Cadherin-2 / CD325 (NCAD) (CDH2/1573), CF568 conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of ~140 kDa, identified as N-Cadherin (NCAD), also known as CD325. N-cadherin is a 140 kDa protein belonging to a family of transmembrane molecules that mediate calcium-dependent intercellular adhesion. Cadherins are involved in controlling morphogenetic movements

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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