Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL

Catalog number BNC681825-100

Price for BNC681825-100

Size / count 1x 100 µL

About this product

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC681825-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SILV
Gene ID: 6490
NCBI Gene ID: 95972
UniProt: P40967
Swiss Prot: P40967
Host: Rabbit
Species Reactivity: Human
Reactivity: Gp100|Melanosome|Pmel17|SILV
Immunogen: Recombinant full-length human SILV protein
Target Antigen: gp100 | Melanosome | Pmel17 | SILV
Clonality: Recombinant Monoclonal
Clone: PMEL/1825R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer
Positive Control: SK-MEL-28 cells or Melanoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 90-100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG, kappa
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF568

Frequently Asked Questions

What is the catalog number for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL?

The catalog number for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL is BNC681825-100.

What sizes are available for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL in stock?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL?

Estimated delivery time for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL?

The safety data sheet for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02a3061270361e104a88/msds/bnc681825-100.pdf.

What is Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF568 conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.