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Product details

VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL

Catalog number BNC881283-100

Price for BNC881283-100

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Size / count 1x 100 µL

About this product

VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15) . This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Reduced expression of VEGI has been reported as a marker of poor prognosis in breast cancer.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881283-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
TNF lig; -related molecule 1 (TL1A) ; Tumor necrosis factor (lig; ) superfamily member 15 (TNFSF15) ; Vascular endothelial growth inhibitor 192a; Vascular endothelial growth inhibitor (VEGI) ; VEGI192A
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TNFSF15
Gene ID
9966
NCBI Gene ID
241382
UniProt
O95150
Swiss Prot
O95150
Host
Mouse
Species Reactivity
Human
Reactivity
VEGI
Immunogen
Recombinant human full-length VEGI fragment
Target Antigen
VEGI
Clonality
Monoclonal
Clone
VEGI/1283
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Angiogenesis, Cancer
Positive Control
Endothelial cells. Colon, intestine, placenta, lung, liver, kidney, pancreas, spleen and prostate.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
22 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL?

The catalog number for VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL is BNC881283-100.

What sizes are available for VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL?

VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL in stock?

VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL?

VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL?

The safety data sheet for VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is VEGI (Vascular Endothelial Growth Inhibitor) (VEGI/1283), CF488A conjugate, 0.1mg/mL used for?

VEGI is an anti-angiogenic cytokine that belongs to tumor necrosis factor superfamily, member 15 (TNFSF15) . This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a l

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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