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Product details

Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL

Catalog number BNC881408-100

Price for BNC881408-100

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Size / count 1x 100 µL

About this product

Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle. Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist, a 34 kDa form and a 29 kDa form. Expression of the 29 kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this MAb reacts with only the 34 kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881408-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Calponin-1; CNN1; Calponin 1 basic smooth muscle; Calponin H1 smooth muscle
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CNN1
Gene ID
1264
NCBI Gene ID
465929
UniProt
P51911
Swiss Prot
P51911
Host
Rabbit
Species Reactivity
Human, Rat
Reactivity
Calponin-1
Immunogen
Recombinant human full-length CNN1 protein
Target Antigen
Calponin-1
Clonality
Recombinant Monoclonal
Clone
CNN1/1408R
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified) |IF (verified) |IHC, FFPE (verified)
Field of Research
Cytoskeleton
Positive Control
Myoepithelial cells in breast ducts
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
34 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG, kappa
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL?

The catalog number for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL is BNC881408-100.

What sizes are available for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL?

Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL in stock?

Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL?

Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Calponin-1 (Smooth Muscle Marker) (CNN1/1408R), CF488A conjugate, 0.1mg/mL used for?

Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing sm

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

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