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Product details

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL

Catalog number BNC881422-500

Price for BNC881422-500

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Size / count 1x 500 µL

About this product

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881422-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NKX2-2
Gene ID
4821
NCBI Gene ID
516922
UniProt
O95096
Swiss Prot
O95096
Host
Rabbit
Species Reactivity
Human
Reactivity
NKX2.2
Immunogen
Recombinant human NKX2.2 protein fragment (exact sequence is proprietary)
Target Antigen
NKX2.2
Clonality
Recombinant Monoclonal
Clone
NX2/1422R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology, Transcription factors
Positive Control
Pancreas or Ewing s sarcoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
40-50 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG, kappa
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL?

The catalog number for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL is BNC881422-500.

What sizes are available for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL in stock?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL?

The safety data sheet for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (NX2/1422R), CF488A conjugate, 0.1mg/mL used for?

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be diff

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

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