Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL

Catalog number BNC881825-100

Price for BNC881825-100

Size / count 1x 100 µL

About this product

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC881825-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: 95kDa melanocyte-specific secreted glycoprotein, M-beta, Melanocyte lineage specific antigen GP100, Melanocyte protein Pmel 17, Melanoma associated ME20 antigen, Melanosomal matrix protein17, p100, p26, PMEL17, Premelanosome protein, Secreted melanoma-associated ME20 antigen, SILV, Silver homolog
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: SILV
Gene ID: 6490
NCBI Gene ID: 95972
UniProt: P40967
Swiss Prot: P40967
Host: Rabbit
Species Reactivity: Human
Reactivity: Gp100|Melanosome|Pmel17|SILV
Immunogen: Recombinant full-length human SILV protein
Target Antigen: gp100 | Melanosome | Pmel17 | SILV
Clonality: Recombinant Monoclonal
Clone: PMEL/1825R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer
Positive Control: SK-MEL-28 cells or Melanoma
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 90-100 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG, kappa
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL?

The catalog number for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL is BNC881825-100.

What sizes are available for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL in stock?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (PMEL/1825R), CF488A conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.