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Product details

PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL

Catalog number BNC941492-500

Price for BNC941492-500

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Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas, and atypical thyroid adenomas. PAX-8 is expressed in the thyroid (and associated carcinomas), non-ciliated mucosal cells of the fallopian tubes, and simple ovarian inclusion cysts, but not normal ovarian surface epithelial cells. PAX-8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas. PAX-8 expression is reported in renal tubules as well as renal cell carcinoma, nephroblastoma, and seminoma. PAX-8 antibody may be used as an additional immunohistochemical marker for renal epithelial tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941492-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Paired box 8; Paired box gene 8; paired box homeotic gene 8; Paired box protein Pax-8; Paired domain gene 8; PAX8
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PAX8
Gene ID
7849
NCBI Gene ID
469728
UniProt
Q06710
Swiss Prot
Q06710
Host
Mouse
Species Reactivity
Human
Reactivity
PAX8
Immunogen
Recombinant human PAX8 fragment (aa60-261) (exact sequence is proprietary)
Target Antigen
PAX8
Clonality
Monoclonal
Clone
PAX8/1492
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Developmental biology
Positive Control
Raji cells. Renal Cell Carcinoma (RCC)
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
62 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL?

The catalog number for PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL is BNC941492-500.

What sizes are available for PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL?

PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL in stock?

PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL?

PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL?

The safety data sheet for PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e1014d7/msds/bnc941492-500.pdf.

What is PAX8 (Renal Cell Marker) (PAX8/1492), CF594 conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 62 kDa, identified as PAX8. It is a member of the paired box (PAX) family of transcription factors. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

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