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Product details

Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL

Catalog number BNC941711-100

Price for BNC941711-100

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Size / count 1x 100 µL

About this product

Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helicalcoiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. The antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941711-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CMD1I; CSM1; CSM2; DES; Intermediate filament protein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
DES
Gene ID
1674
NCBI Gene ID
594952
UniProt
P17661
Swiss Prot
P17661
Host
Mouse
Species Reactivity
Chicken, Hamster, Human, Mouse, Rat
Reactivity
Desmin
Immunogen
Recombinant human full-length desmin protein
Target Antigen
Desmin
Clonality
Monoclonal
Clone
DES/1711
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
SJRH30 Cells. Uterus or Leiomyosarcoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
52 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL?

The catalog number for Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL is BNC941711-100.

What sizes are available for Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL?

Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL in stock?

Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL?

Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Desmin (Muscle Cell Marker) (DES/1711), CF594 conjugate, 0.1mg/mL used for?

Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain alpha-helicalcoiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguish

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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