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Product details

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL

Catalog number BNC941836-500

Price for BNC941836-500

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Size / count 1x 500 µL

About this product

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941836-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Homeobox protein NK-2 homolog B, NK2 transcription factor like protein B, NK2 transcription factor related locus 2, NKX22, Nkx2b, tinman
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
NKX2-2
Gene ID
4821
NCBI Gene ID
516922
UniProt
O95096
Swiss Prot
O95096
Host
Mouse
Species Reactivity
Chicken, Human, Mouse, Rat
Reactivity
NKX2.2
Immunogen
Human full-length recombinant NKX2.2 protein
Target Antigen
NKX2.2
Clonality
Recombinant Monoclonal
Clone
RNX2/294
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Developmental biology, Transcription factors
Positive Control
Pancreas or Ewing s sarcoma
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
40-50 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL?

The catalog number for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL is BNC941836-500.

What sizes are available for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL in stock?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL?

NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL?

The safety data sheet for NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NKX2.2 (Neuroendocrine & Ewing s Sarcoma Marker) (rNX2/294), CF594 conjugate, 0.1mg/mL used for?

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be diff

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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