MICU2 Recombinant Rabbit Monoclonal Antibody [PSH01-84]

Catalog number HA721742

Price for HA721742

Size / count 100 µL

About this product

Enables protein heterodimerization activity. Involved in calcium import into the mitochondrion and negative regulation of mitochondrial calcium ion concentration. Located in mitochondrial inner membrane and mitochondrial intermembrane space. Part of uniplex complex. Key regulator of mitochondrial calcium uniporter (MCU) required to limit calcium uptake by MCU when cytoplasmic calcium is low. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, depending on the concentration of calcium. MICU2 acts as a gatekeeper of MCU that senses calcium level via its EF-hand domains: prevents channel opening at resting calcium, avoiding energy dissipation and cell-death triggering.

Specifications

Catalog number: HA721742
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: 1110008L20Rik antibody EF hand domain containing family member A1 antibody EF hand domain family A1 antibody EF hand domain family member A1 antibody EF-hand domain-containing family member A1 antibody EFHA1 antibody EFHA1 EF hand domain family member A1 antibody EFHA1_HUMAN antibody FLJ25016 antibody FLJ34588 antibody Smhs2 homolog antibody
Abbreviation: MICU2, EFHA1
Swiss Prot: Q8IYU8 Human, Q8CD10 Mouse, Q99P63 Rat
Cellular Locus: Mitochondrion
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human MICU2 aa 23-434.
Isotype: IgG
Clone: PSH01-84
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IF-Tissue, FC
Positive Control: LNCaP cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, human kidney tissue lysate, human liver tissue lysate, mouse heart tissue lysate, mouse kidney tissue lysate, rat kidney tissue lysate, human heart tissue, human kidney tissue, human liver tissue, mouse heart tissue, rat kidney tissue, LNCaP.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:200-1:1,000 ;IF-Tissue: 1:200 ;FC: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 50 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for MICU2 Recombinant Rabbit Monoclonal Antibody [PSH01-84]?

The catalog number for MICU2 Recombinant Rabbit Monoclonal Antibody [PSH01-84] is HA721742.

What sizes are available for MICU2 Recombinant Rabbit Monoclonal Antibody [PSH01-84]?

MICU2 Recombinant Rabbit Monoclonal Antibody [PSH01-84] is available in the following size(s): 100 µL.

Is MICU2 Recombinant Rabbit Monoclonal Antibody [PSH01-84] in stock?

MICU2 Recombinant Rabbit Monoclonal Antibody [PSH01-84] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MICU2 Recombinant Rabbit Monoclonal Antibody [PSH01-84] used for?

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.