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Product details

CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL

Catalog number BNCB0391-500

Price for BNCB0391-500

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Size / count 1x 500 µL

About this product

This antibody recognizes a protein of 26 kDa, identified as CD81 (Workshop VI; Code CD81.1) . CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelets are negative, while monocytes are variably positive. CD81 is a member of a family of tetraspanin transmembrane proteins, including CD9, CD37, CD53, CD63, and CD82. It associates with CD19, CD21, Leu 13, and integrins on cell membrane and is involved in signal transduction in B lymphocyte development and cell adhesion. CD81 also acts as a receptor for the envelope protein E2 of chronic hepatitis C virus. Antibodies to CD81 have anti-proliferative effects on different lymphoid cell lines, particularly those derived from large cell lymphomas. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB0391-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD81; Target of the antiproliferative antibody 1 (TAPA-1) ; Tetraspanin-28; Tspan-28
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD81
Gene ID
975
NCBI Gene ID
54457
UniProt
P60033
Swiss Prot
P60033
Host
Mouse
Species Reactivity
Human, Rat
Reactivity
CD81|TAPA-1
Immunogen
B-Cell line derived from a Burkitt lymphoma
Target Antigen
CD81 | TAPA-1
Clonality
Monoclonal
Clone
1.3.3.22
Type
Primary
Source
Animal
Origin
Animal
Applications
Functional studies (published) |Exosome staining (verified) |Flow, surface (verified) |IF (verified) |IHC, FFPE (verified) |WB (published)
Field of Research
Exosomes/EVs, Immunology
Positive Control
Ramos, Daudi, Raji, U266, HUT-78, HUT-102, Jurkat, HL-60, KG1a, A293, A431, MG63, MCF-7, and human lymphocytes. Tonsil or liver tissue.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
26 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Hepatology (2008) 48(6): 1761. (functional studies) Microbiol Immunol (2004) 48(5): 417–426. (western)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL?

The catalog number for CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL is BNCB0391-500.

What sizes are available for CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL?

CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL in stock?

CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL?

CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD81 / TAPA-1 (1.3.3.22), Biotin conjugate, 0.1mg/mL used for?

This antibody recognizes a protein of 26 kDa, identified as CD81 (Workshop VI; Code CD81.1) . CD81 has a very broad cellular distribution, being expressed on T- and B-lymphocytes, NK cells, thymocytes, eosinophils, fibroblasts, epithelial and endothelial cells. Neutrophils, erythrocytes and platelet

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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