Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL — image 1 of 3

Product details

Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1475-500

Price for BNCB1475-500

Size / count 1x 500 µL

About this product

Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Bcl-6 allows GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. Antibodies to Bcl-6 are helpful in a number of diagnostic settings, for example in the differential diagnosis of small B-cell lymphoma, and in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) .Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB1475-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Bcl-6; B-Cell Lymphoma 6 Protein; B-cell lymphoma 5 protein; Zinc Finger Protein 51; zinc finger transcription factor BCL6S; BCL6 Transcription Repressor
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: BCL6
Gene ID: 604
NCBI Gene ID: 478588
UniProt: P41182
Swiss Prot: P41182
Host: Mouse
Species Reactivity: Human
Reactivity: Bcl-6
Immunogen: Recombinant human bcl-6 protein fragment (aa256-389) (exact sequence is proprietary)
Target Antigen: Bcl-6
Clonality: Monoclonal
Clone: BCL6/1475
Type: Primary
Source: Animal
Origin: Animal
Applications: WB (verified)
Field of Research: Apoptosis, Cancer, Immunology, Transcription factor
Positive Control: Raji or Ramos cells. Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 95 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL?

The catalog number for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL is BNCB1475-500.

What sizes are available for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL?

Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL in stock?

Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL?

Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Bcl-6 (Follicular Lymphoma Marker) (BCL6/1475), Biotin conjugate, 0.1mg/mL used for?

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.