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Product details
Catalog number BNCB1486-500
Price for BNCB1486-500
Size / count 1x 500 µL
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST s), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97.8 percent of scorable GIST s, including all c-kit negative GIST s. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GIST s is nearly identical: 94.4% vs. 94.7%.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (DG1/1486), Biotin conjugate, 0.1mg/mL is BNCB1486-500.
DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (DG1/1486), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (DG1/1486), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (DG1/1486), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (DG1/1486), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (DG1/1486), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e10186f/msds/bncb1486-500.pdf.
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST s), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been repor
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
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